Wake Forest and Virginia Tech will play in Blacksburg on Saturday afternoon. The Hokies got off to a slow start, but are turning things around as ACC play gets into full swing. Can the Hokies hold serve at home to get to .500 for the year? Here, I attempt to answer that question and bring you my Wake Forest vs Virginia Tech prediction for Saturday’s game.
Our Wake Forest vs Virginia Tech Pick
- Pick: Virginia Tech –6.5
- Confidence: 3/5
Game Snapshot
- Matchup: Wake Forest Demon Deacons vs Virginia Tech Hokies
- Date & Time: Saturday, October 4, 2025, at 1:00 PM ET
- Venue: Lane Stadium, Blacksburg, VA
- Broadcast: The CW Network
Wake Forest vs Virginia Tech Odds
| Spread | Moneyline | Total |
|---|---|---|
| Virginia Tech –6.5 | Wake +190 / Va Tech -225 | 52.5 |
Key Storylines
- Momentum shift under new coaching: Virginia Tech replaced Brent Pry after an 0–3 start, elevating Phillip Montgomery to interim head coach. The Hokies have responded with back-to-back wins over Wofford and NC State. Their rushing attack exploded in that game against the Wolfpack and the Hokies’ confidence is growing.
- Wake Forest struggling in ACC play: Wake Forest is 0-2 in ACC play coming into this week. The Demon Deacons opened their season with non-conference wins against Kennesaw State and FCS Western Carolina. But they have lost to Georgia Tech and NC State and could really use a conference win.
- Defensive weaknesses: Wake Forest has allowed at least 30 points in each of their ACC games to begin conference play. Virginia Tech has given up over 40 points to Old Dominion and Vanderbilt already this year. Either defense is more than capable of laying an egg in this matchup and will need to avoid that to win in Week 6.
Quarterback Play
Virginia Tech’s signal-caller is Kyron Drones. In the win over NC State, Drones completed 20 of 34 passes for 177 yards and two touchdowns, while avoiding turnovers. He has eight touchdown passes to three interceptions and is playing better over the last couple of weeks.
- Wake Forest’s quarterback is Robby Ashford. Ashford has just one touchdown pass through four weeks and has to do more if the Demon Deacons are going to get their first conference win of the 2025 season.
Betting Trends & H2H
- Wake Forest is 2-2 against the spread so far this season.
- Virginia Tech is 1-4 against the spread through their first five games.
- Wake Forest is 2-2 on over/unders for the season.
- Three of Virginia Tech’s five games have stayed under their totals.
Wake Forest vs Virginia Tech Model Projection
Score Projection: Virginia Tech 27 – Wake Forest 17
Win Probability: Virginia Tech 68%, Wake Forest 32%
Final Thoughts
Virginia Tech enters this game playing better football than Wake Forest, which has looked dismal in conference play. The Hokies haven’t been great against the spread so far this year. But they are likely to cover the number by putting up more points than usual against a Wake Forest defense that has been torched by each of their first two ACC opponents.
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Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.
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- Source: https://ats.io/college-football/wake-forest-demon-deacons-vs-virginia-tech-hokies-pick-prediction-10-4-2025/469673/