The Tulsa Golden Hurricane and Memphis Tigers will meet on Saturday night in college football. Tulsa is 2-3 on the season but has a win over Oklahoma State under their belt this season. They will try to upset an unbeaten Memphis team in this contest, but the Tigers are a huge home favorite here. Before kickoff from Memphis, you can continue reading to find my Tulsa vs Memphis prediction.
Our Tulsa vs Memphis Pick
- Pick: Over 54.5
- Confidence: 4/5
Game Snapshot
- Matchup: Memphis Tigers vs Tulsa Golden Hurricane
- Date & Time: Saturday, October 4, 2025, 8:00 PM EDT
- Venue: Simmons Bank Liberty Stadium, Memphis, TN
- Broadcast: ESPNU
Key Storylines
Memphis Tigers: Memphis enters this game with an undefeated 5-0 record. They have a dominant run game that ranks 11th nationally with 247.2 rushing yards per game. Running backs Sutton Smith and Greg Desrosiers Jr. have been exceptional, earning back-to-back Doak Walker National Running Back of the Week honors. Quarterback Brendon Lewis has been effective with both passing and rushing touchdowns under his belt this year. He is a big reason for the team’s 39.6 points per game average. Memphis has been impressive defensively as well. They are allowing only 91.4 rushing yards per game, ranking 11th nationally.
Tulsa Golden Hurricane: Tulsa has a 2-3 record under first-year head coach Tre Lamb. The team has shown flashes of potential, including a notable upset over Oklahoma State. But their consistency has been an issue, particularly on offense, where quarterback play has been uncertain. That upset win over Oklahoma State has also not aged well, given how bad the Cowboys have played so far this year. Tulsa’s offensive line has struggled as well and they will try to do a better job of protecting the quarterback. The Golden Hurricane’s run-heavy approach, led by Dominic Richardson, faces a formidable Memphis run defense.
Betting Trends & H2H
- Memphis: The Memphis Tigers are 5-0 straight up and against the spread in 2025.
- Tulsa: Tulsa is 2-3 straight up and against the spread in 2025.
- Over/Under: Memphis games have hit the over in three of five games this season. Tulsa games have hit the over just once in five games this season.
- Head-to-Head: Memphis has won its last three meetings against Tulsa.
Tulsa vs Memphis Model Projection
Score Projection: Memphis 38 – Tulsa 21
Win Probability: Memphis 85%, Tulsa 15%
Final Thoughts
Memphis enters this game as a heavy favorite, and for good reason. Their explosive offense and stout defense will present significant challenges for a Tulsa team still finding its footing under a new coaching staff. I think that this game is going to be lopsided for the most part. But my best bet for this game is for the over to cash at 54.5 points, as Memphis should do a lot of scoring and Tulsa should do just enough to get this contest to the total.
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- Source: https://ats.io/college-football/tulsa-golden-hurricane-vs-memphis-tigers-pick-prediction-10-4-2025/469779/