The San Francisco Giants and Los Angeles Dodgers will face off in an NL West matchup on Thursday night at Dodger Stadium. The Dodgers are trying to protect their position atop the NL West standings, while the Giants are still fighting for their playoff lives. Here, I break down this contest in the NL West and give you my Giants vs Dodgers prediction for tonight.
Our Giants vs Dodgers Pick
- Pick: Under 7.5
- Confidence: 3/5
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Game Snapshot
- Matchup: San Francisco Giants vs. Los Angeles Dodgers
- Date & Time: Thursday, September 18, 2025, 10:10 PM EDT
- Starting Pitchers: Logan Webb (SF) vs. Yoshinobu Yamamoto (LAD)
- Stadium: Dodger Stadium, Los Angeles, CA
- Broadcast: MLB Network
Key Storylines
Pitching Matchup
Logan Webb (14-10, 3.34 ERA) will take the mound for the Giants in this game. While Webb has been a reliable starter this season, he struggled in his last outing against the Dodgers. Webb allowed six runs in just over four innings in that game. He will look to rebound against a potent Los Angeles lineup.
Los Angeles’ Yoshinobu Yamamoto (11-8, 2.66 ERA) has been a standout on the mound for the Dodgers. He enters this game with a streak of three consecutive starts featuring at least 10 strikeouts and seven innings pitched. His dominance on the mound has been a key factor in the Dodgers’ success this season.
Playoff Update
The Giants come into this game two games back of the final Wild Card spot in the National League. They will need to overtake the Cincinnati Reds, Arizona Diamondbacks, and New York Mets if they want to qualify for the postseason.
The Dodgers enter Thursday with a two-game lead over the San Diego Padres in the NL West standings. Los Angeles has to keep winning to avoid letting San Diego overtake them for the division lead during the final stretch of the regular season.
Recent Team Streaks
The Giants snapped a four-game losing streak with a dramatic 5-1 win over the Arizona Diamondbacks in 11 innings on Wednesday. Christian Koss delivered a crucial two-run double during a five-run explosion in the 11th inning, providing a much-needed boost to the team’s morale. The Dodgers are coming off a 5-0 win over the Philadelphia Phillies. That win snapped a two-game losing streak and the Dodgers will look for a second win in a row here.
Best Player Props
| Player | Prop |
|---|---|
| Yoshinobu Yamamoto | Over 7.5 strikeouts |
| Michael Conforto | Under 1.5 Total Bases |
| Shohei Ohtani | Over 0.5 home runs |
Betting Trends & H2H
- The Dodgers hold a 6-3 lead going into this series opener from Los Angeles.
- The Dodgers have won their last two meetings with the Giants going into this contest.
- The Dodgers are 49-28 at home in 2025.
- San Francisco is 38-39 on the road for the season.
Giants vs Dodgers Model Projection
- Score Projection: Giants 3 – Dodgers 4
- Win Probability: Giants 34%, Dodgers 66%
Final Thoughts
This is the biggest game of the night in MLB in terms of playoff significance. Both teams have plenty to play for in this game. And while I think the Dodgers will ultimately get the win, my best bet is for this game to stay under the total. Yamamoto is on fire on the mound for LA and Logan Webb is pitching well himself for the most part. Expect a low-scoring game here that will have playoff-like intensity throughout.
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- Source: https://ats.io/mlb/san-francisco-giants-vs-los-angeles-dodgers-prediction-9-18-2025/467321/