Purdue and Minnesota will meet in Big Ten play on Saturday night. Purdue is 2-3 on the season and will try to steal a game on the road against the 3-2 Golden Gophers. Minnesota is looking to bounce back from a loss to Ohio State in their last outing. Before kickoff from Minneapolis, continue reading to get my Purdue vs Minnesota prediction.
Our Purdue vs Minnesota Pick
- Pick: Minnesota -7.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Purdue Boilermakers vs Minnesota Golden Gophers
- Date & Time: Saturday, October 11, 2025, 7:30 PM ET
- Venue: Huntington Bank Stadium, Minneapolis, MN
- Broadcast: Big Ten Network
Purdue vs Minnesota Odds
| Betting Market | Odds |
|---|---|
| Spread | MIN -7.5 |
| Moneyline | MIN -300, PUR +250 |
| Total | 48.5 |
Key Storylines
- Purdue’s Defensive Struggles: The Boilermakers have allowed an average of 29.8 points and 397.6 yards per game this season. Their defense ranks 76th against the run and 105th against the pass nationally, which Minnesota’s offense could exploit.
- Drake Lindsey’s Leadership: Minnesota’s quarterback, Drake Lindsey, is expected to capitalize on Purdue’s defensive weaknesses in their secondary. The Boilermakers have been lit up by all of the power conference competition they have faced this season and the Golden Gophers will try to join that list.
- Homecoming Momentum: Minnesota enters this game with a 3-0 record at home this season, providing a strong psychological advantage as they look to rebound from a tough loss to Ohio State in Columbus.
Quarterback Play
Purdue quarterback Ryan Browne has thrown for 1,338 yards and seven touchdowns this season. But he has thrown five interceptions and could struggle with a challenging matchup against Minnesota’s defense. Minnesota’s Drake Lindsey has thrown seven touchdown passes and two interceptions this year. He will try to bounce back after Minnesota was held without a touchdown against Ohio State.
Betting Trends & H2H
- Against the Spread: Minnesota is 1-4 against the spread for the season. Purdue is 2-3 against the spread for the year.
- Home/Away Splits: Minnesota has a perfect 3-0 record at home this season, while Purdue has struggled in their lone road game of the year.
- Over/Under Trends: The total has gone under in three of Purdue’s first five games. Minnesota is 3-1-1 to the over heading into this week.
Purdue vs Minnesota Model Projection
Score Projection: Minnesota 31 – Purdue 20
Win Probability: Minnesota 72%, Purdue 28%
Final Thoughts
Considering Purdue’s defensive vulnerabilities and Minnesota’s strong home performances, the Golden Gophers are well-positioned to cover the spread in this matchup in my opinion. The Boilermakers’ defensive struggles are likely to be their undoing against a Minnesota team eager to rebound from a tough loss to the top team in the country. I’ll lay the points with Minnesota in their homecoming game on Saturday night.
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- Source: https://ats.io/college-football/purdue-boilermakers-vs-minnesota-golden-gophers-pick-prediction-10-11-2025/470677/