The Carolina Panthers will take on the San Francisco 49ers on Monday Night Football at 8:15 p.m. ET tonight, and you can access the top NFL betting promotions for the game. Get the best sign-up deals today from leading online sportsbooks, including bet365, FanDuel, Fanatics Sportsbook, BetMGM, and Caesars Sportsbook.
Together, the top Panthers vs. 49ers NFL betting promotions offer over $3,800 in bonuses. Leverage these promotions by clicking on the sign-up options below.
NFL Betting Promotions: Monday, November 24, 2025
See the chart below for more details on the five best Panthers vs. 49ers NFL betting promotions to claim for Monday Night Football betting.