Looking for Panthers vs. 49ers anytime touchdown odds to bet on tonight? If so, you’ve come to the right place, as those odds are highlighted in this piece. Additionally, I give you the best NFL betting promos to sign up with today to bet on the action. I round out this article with my own Panthers vs. 49ers anytime touchdown odds picks and predictions.
The Carolina Panthers are one of the surprising teams in the NFL this season at 6-5, with a chance to take first place in the NFC South. They have a tough matchup against the 7-4 San Francisco 49ers, who are finally fully healthy on offense, and have the always dangerous Christian McCaffrey ready to strike. With that being said, let’s get into Panthers vs. 49ers anytime touchdown odds ahead of tonight’s kickoff oat 8:15 p.m. ET on ESPN.
Christian McCaffrey Anytime Touchdown Odds
McCaffrey is the player attracting most of the attention entering Monday Night Football due to his storied past with the Panthers. The superstar running back started his career in Carolina as a first round pick in 2017 before being traded to the 49ers midway through the 2022 season. Seeing as McCaffrey is the most pivotal player on the 49ers’ offense, it isn’t surprising to see him have the shortest Panthers vs. 49ers anytime touchdown odds of any player.
- Christian McCaffrey Anytime Touchdown Odds on bet365 Sportsbook: (-350)
Panthers vs. 49ers Anytime Touchdown Odds
Here are the ten players to consider placing a Panthers vs. 49ers anytime touchdown odds bet on. Like the McCaffrey anytime touchdown odds above, odds come from bet365 Sportsbook and are subject to change:
- Christian McCaffrey (-350)
- Rico Dowdle (-140)
- George Kittle (+140)
- Tetairoa McMillan (+150)
- Jauan Jennings (+210)
- Ricky Pearsall (+210)
- Brock Purdy (+400)
- Jalen Coker (+400)
- Xavier Legette (+400)
- Brian Robinson Jr. (+425)
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Panthers vs. 49ers Picks and Predictions
Now it’s time to discuss my Panthers vs. 49ers anytime touchdown odds picks and predictions. See the three players I’m backing most to find the end zone tonight below in this intriguing NFC clash on MNF.
Christian McCaffrey (-350)
It would be a stunner if McCaffrey doesn’t get ample chances to score against his old team. Outside of the narrative being too good to pass up, McCaffrey has scored 11 times this season, and has had a massive workload in both the receiving game, and on the ground. Carolina’s rushing defense has been respectable enough in 2025, but McCaffrey is the safest pick to make tonight. Sign up with the DraftKings promo code and get $300 in bonus bets if your $5+ first bet on McCaffrey to find the end zone tonight wins.
Tetairoa McMillan (+150)
Tetairoa McMillan is the first of my two Panthers vs. 49ers anytime touchdown odds that are slightly bigger risks than McCaffrey was. Outside of McMillan, the Panthers don’t have much playmaking at the wide receiver position. The 49ers’ defense has done a commendable job in 2025, considering the mass exodus of talent in the offseason, and mass injuries suffered this season. But I’d be shocked if McMillan doesn’t score, especially if Bryce Young plays a good game. Register with the bet365 bonus code HANDLE and get $150 in bonus bets when your $5+ first bet on McMillan settles, win or lose.
Ricky Pearsall (+210)
My riskiest pick amongst Panthers vs. 49ers anytime touchdown odds tonight is Ricky Pearsall, but I love this pick at this price. Pearsall passes the eye test of being a fluid route runner, has good hands, and is hard to bring down after the catch. He hasn’t has the chance to light up the stat sheet this season because of injury, but I think a strong close to his season is in order. Having the rest of the 49ers’ offense healthy at the same time should only help him. Redeem the Fanatics Sportsbook promo code HANDLE today to place your first of 10 No Sweat Bets on Pearsall to strike pay dirt.
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- Source: https://sportshandle.com/panthers-vs-49ers-anytime-touchdown-odds-betting-promos-picks-and-predictions/