Middle Tennessee vs Delaware Pick & Prediction – 10/22/2025

The Middle Tennessee Blue Raiders will visit the Delaware Blue Hens on Wednesday night in college football action. The Blue Hens are off to a respectable start to their first season of FBS football. They will try to continue playing well against a Middle Tennessee team that has been one of the worst in FBS competition. Before kickoff from Delaware, continue reading for my Middle Tennessee vs Delaware prediction.

Our Middle Tennessee vs Delaware Pick

• Pick: Delaware -9.5
• Confidence: ★★★★☆

Game Snapshot

• Matchup: Middle Tennessee Blue Raiders vs Delaware Fightin’ Blue Hens
• Date & Time: Wednesday, October 22, 2025, 7:30 p.m. ET
• Venue: Tubby Raymond Field at Delaware Stadium, Newark, DE
• Broadcast: ESPN2

Middle Tennessee vs Delaware Odds

Key Storylines

Delaware enters this game with an offense that’s looked respectable in its first FBS season. Quarterback Nick Minicucci has compiled over 1,800 passing yards, nine touchdowns, and just three interceptions so far. Their passing attack averages roughly six yards per play, while Middle Tennessee’s pass defense surrenders nearly 7.1 yards per attempt, ranking in the bottom third of the FBS.

Middle Tennessee has struggled to generate offense. They are averaging just 17 points per game and rank 133rd nationally in scoring. Their rushing game has averaged 82.8 yards per game, placing them 134th in the country. Middle Tennessee will need to find some chunk plays if they want a shot at ending their three-game losing streak.

The Blue Hens give up 28.3 points per game. That is far from elite, but is solid when compared to the struggling defense of the Blue Raiders. And with Delaware having home-field advantage, the Blue Hens will be expected to outperform MTSU on defense here.

Quarterback Play

Delaware’s Minicucci is the engine for his team’s offense. His completion percentage hovers in the low 60s and his 3/1 touchdown-to-interception ratio speaks to his efficiency. Minicucci has been very good to lead his team to a respectable debut season at this level of competition.

Middle Tennessee signal-caller Nicholas Vattiato has posted decent numbers. He has a 61.1% completion rate, eight touchdowns, and four interceptions. But the surrounding supporting cast and offensive line haven’t provided much in the way of help. The Blue Raiders’ pass offense averages only 6.1 yards per attempt, ranking in the bottom quartile nationally.

Betting Trends & H2H

• Delaware is 2-3-1 against the spread on the season.
• Middle Tennessee is 2-4 against the spread this year.
• The Blue Hens are 2-3-1 on over/unders going into this week’s game.
• Middle Tennessee has gone under the total in four of their first six games.
• Delaware has a 2-0 lead in their all-time series against Middle Tennessee. These programs have not played since 1978.

Middle Tennessee vs Delaware Model Projection

Score Projection: Delaware 31 – Middle Tennessee 18

Win Probability: Delaware 75%, Middle Tennessee 25%

Final Thoughts

Delaware should have a clear advantage in this matchup with Middle Tennessee. The Blue Hens are more consistent moving the ball through the air and the Blue Hens’ defense is more reliable as well. I’ll lay the points with Delaware in this mid-week Conference USA contest.

Jay Sanin

Jay Sanin is a sports bettor, writer and broadcaster from New York. He is an avid New York Knicks fan and is no longer ashamed to admit it. He is also an avid New York Giants fan, and is very ashamed to admit it. His top sports to handicap are the NBA, WNBA and men’s tennis for some reason. He has watched more UAlbany Great Danes basketball than anyone should consume.

• SCCG Management. The Gambling Industry’s Global Connector. Access Here.
• Source: https://ats.io/college-football/middle-tennessee-blue-raiders-vs-delaware-blue-hens-pick-prediction-10-22-2025/471846/