The Baltimore Ravens will host the Los Angeles Rams in Week 6 of the 2025 NFL season on Sunday. Both teams took losses in Week 5 and will try to bounce back in this contest. The Ravens are dealing with some key injury concerns going into this matchup, while the Rams will hope that some extra rest helps them get back into the win column. Before kickoff from Baltimore, continue reading to get my Rams vs Ravens prediction for Sunday.
Our Rams vs Ravens Pick
- Pick: Los Angeles Rams -7.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Los Angeles Rams vs Baltimore Ravens
- Date & Time: Sunday, October 12, 2025, at 1:00 PM EDT
- Venue: M&T Bank Stadium, Baltimore, MD
- Broadcast: FOX
Rams vs Ravens Odds
| Betting Market | Odds |
|---|---|
| Spread | Rams -7.5 |
| Moneyline | Rams -425, Ravens +320 |
| Total | 45.5 |
Key Storylines
- Rams’ Search For Consistency: The Rams have dropped two of their last three games going into Week 6. They lost at home on Thursday Night Football against the San Francisco 49ers last week, despite the Niners relying on backup quarterback Mac Jones in that game. Los Angeles needs to take better care of the football and execute in key situations to avoid another loss here.
- Ravens’ Quarterback Situation: The uncertainty surrounding Lamar Jackson’s availability due to injury has left the Ravens’ offense in flux. Jackson is expected to miss another couple of games. Backup quarterback Cooper Rush struggled in his place in Week 5 and will need to be better if the Ravens are going to avoid dropping to 1-5 on the year.
- Ravens’ Defensive Challenges: Baltimore’s defense has been underperforming this season. They have allowed over 35 points in four of their first five games this season and have to get more stops to help the Ravens compete in Jackson’s absence.
- Rest Advantage: The Rams have some extra rest going into this game after playing on Thursday night. They will try to use that to their advantage against the banged-up Ravens.
Quarterback Play
Matthew Stafford is averaging just over 300 passing yards per game this season. The Rams as a whole have struggled to find consistency, but Stafford has been excellent this year for Los Angeles. Baltimore went with Cooper Rush in Jackson’s place last time out. He threw three interceptions and failed to throw a touchdown pass in the Ravens’ 44-10 loss to the Texans.
Betting Trends
- Rams’ Road Performance: The Rams are 1-1 on the road so far this season.
- Ravens’ Home Record: Baltimore has struggled at home, with a 1-2 record at M&T Bank Stadium this season.
- Over/Under Trends: All five Ravens games this season have gone over their totals. The Rams are 3-2 to the over on the year.
- ATS Trends: Los Angeles is 3-2 against the spread so far this season. Baltimore is 1-4 against the spread going into Week 6.
Rams vs Ravens Model Projection
- Score Projection: Rams 27 – Ravens 17
- Win Probability: Rams 65%, Ravens 35%
Final Thoughts
With Lamar Jackson injured, the Ravens will be more one-dimensional on offense than usual. That should help the Rams’ defense to do a better job of getting off the field, giving Stafford and the Los Angeles offense more chances to put up points. I’ll lay the points with the Rams here, as the Ravens’ miserable start to the season should continue.
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- Source: https://ats.io/nfl/los-angeles-rams-vs-baltimore-ravens-prediction-10-12-2025/469946/