The Los Angeles Dodgers (88-68) will visit the Arizona Diamondbacks (79-77) on Tuesday night. Los Angeles has already clinched a postseason berth and is chasing the NL West crown. Arizona is fighting for a Wild Card spot, trailing by just one game entering this series. Before these teams play this huge game in Phoenix, continue reading to get my thoughts, including my Dodgers vs Diamondbacks prediction.
Our Dodgers vs Diamondbacks Pick
- Pick: Los Angeles Dodgers Moneyline
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Los Angeles Dodgers vs Arizona Diamondbacks
- Date & Time: Tuesday, September 23, 2025, 9:40 PM EDT
- Starting Pitchers: Shohei Ohtani (Dodgers) vs Brandon Pfaadt (Diamondbacks)
- Stadium: Chase Field, Phoenix, AZ
- Broadcast: MLB.tv
Key Storylines
- Pitching matchup: Shohei Ohtani is only 1-1 in decisions this season, but brings an ERA of 3.29 and has shown flashes of dominance since returning to pitching this year. His ability to generate strikeouts and limit damage could be key against Arizona. The Diamondbacks’ Brandon Pfaadt has more wins (13-8) but a higher ERA (5.02). He could have a tough time against the dangerous lineup of the Dodgers here.
- Key Players:
- Shohei Ohtani: Ohtani can carry the Dodgers on the mound and contribute at the plate in this game.
- Corbin Carroll: Carroll is the Diamondbacks’ star and just became the first in franchise history to join the 30/30 club.
- Geraldo Perdomo: Geraldo Perdomo leads Arizona in batting average and OBP. He is strong in clutch situations for the D-Backs.
- Recent team streaks:
- Arizona has won two games in a row and a third straight win would be huge for their playoff hopes.
- Los Angeles had an extended winning streak snapped in their series finale against the San Francisco Giants on Sunday.
Best Player Props
| Player | Prop | Pick |
|---|---|---|
| Shohei Ohtani | Strikeouts | Over 5.5 |
| Corbin Carroll | Home Runs | Over 0.5 |
| Geraldo Perdomo | Total Bases | Under 1.5 |
Betting Trends & H2H
- The season series between these teams is tied 5-5.
- Arizona has won two of the last three games played between these teams.
- The Dodgers are 34-15 against NL West opponents this season.
- Arizona is 25-21 against division foes during the 2025 MLB season.
Dodgers vs Diamondbacks Model Projection
- Score Projection: Dodgers 6 – Diamondbacks 4
- Win Probability: Dodgers 65%, Diamondbacks 35%
Final Thoughts
As far as I’m concerned, the Dodgers look like the safer bet in this game. The Dodgers have a better starting pitcher, a more consistent offense, and an opportunity to get closer to locking up the NL West. Arizona is dangerous, especially with players like Carroll and Perdomo capable of big offensive performances, but Pfaadt’s elevated ERA will be their undoing tonight. I recommend betting the Dodgers in this huge game out West.
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- Source: https://ats.io/mlb/los-angeles-dodgers-vs-arizona-diamondbacks-prediction-9-23-2025/468092/