The Detroit Lions and Washington Commanders meet once more after last season’s playoff upset, but the circumstances have changed. Our Lions vs. Commanders Predictions for Week 10 highlight Detroit’s potential to rebound, Washington’s offensive challenges, and several promising prop bets.
*Sports betting is unpredictable, and while these NFL picks are based on data and matchup trends, outcomes can always differ.
Lions vs. Commanders – Week 10 Game Overview
The Lions enter this matchup at 5-3, eager to rebound after a tough home loss. They have consistently played well following losses, having covered the spread in 12 straight games afterward. Their offense is among the most efficient in the league, and their pass rush ranks second in total sacks.
Washington, however, has lost four straight, with the last three games having large margins. Key injuries have significantly weakened both sides of the ball. QB Jayden Daniels is out with a dislocated elbow, putting Marcus Mariota in the starting role. Top corner Marshon Lattimore and WR Luke McCaffrey are also sidelined, leaving the team thin at key positions.
This game is a rematch of last year’s NFC Divisional Round where Washington pulled off an upset, but the current conditions make a repeat outcome unlikely. Detroit holds a clear advantage in health, execution, and offensive consistency.
Lions to Cover the Spread -8.5
Detroit has a strong track record following losses, consistently bouncing back with urgency and sharper execution. Their offense matches up well against Washington’s depleted defense, especially with the Commanders missing Lattimore in the secondary. With Washington struggling to score and sustain drives during their losing streak, Detroit’s balanced offense and pass rush should allow them to control the game effectively.
Lions Over 3.5 Team Touchdowns
The Lions boast one of the NFL’s most complete offensive units, with multiple playmakers both in the run and pass game. After being held in check last week, a strong rebound performance is expected. Washington’s defense has allowed multiple big scoring games recently, and Detroit’s pace and red zone efficiency point toward four or more touchdowns.
Jahmyr Gibbs Over 70.5 Rushing Yards
Gibbs was limited last week, but this matchup favors a bounce-back performance. Washington has struggled against the run during their losing streak, and with Detroit likely playing with a lead, Gibbs should see steady volume. His ability to break long runs provides upside to clear this number even on moderate touches.
Marcus Mariota Under 205.5 Passing Yards
Mariota steps in for the injured Jayden Daniels, but Washington’s passing game has already been limited due to turnovers and inconsistent execution. With key receiving weapons sidelined and Detroit’s pass rush among the league’s best, Mariota is likely to operate in a conservative, run-first approach. This situation favors the Under on his passing yards.
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