The Kennesaw State Owls will visit the Indiana Hoosiers in Week 2 of the college football season on Saturday. Indiana is a massive favorite in their second game of the year and they will look to avoid an upset against a Kennesaw State team in its second year of FBS competition. Before the action begins in Indiana, continue reading to get my Kennesaw State vs Indiana prediction in college football.
Our Kennesaw State vs Indiana Pick
- Pick: Over 52.5
- Confidence: 3/5
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Game Snapshot
- Matchup: Kennesaw State Owls vs Indiana Hoosiers
- Date & Time: Saturday, September 6, 2025, 12:00 PM ET
- Venue: Memorial Stadium, Bloomington, IN
- Broadcast: Fox Sports 1
Kennesaw State vs Indiana Odds
| Spread | Total |
|---|---|
| Indiana −36.5 | 52.5 |
Key Storylines
Kennesaw State nearly stunned Wake Forest in Week 1. They lost 10–9 in a defensive slugfest against the Demon Deacons. The Owls’ run defense impressed by holding Wake Forest to just 2.8 yards per carry. But the Owls’ offense remains inefficient as quarterback Dexter Williams completed just 36% of his passes for 149 yards.
Indiana’s offense churned out over 500 total yards against Old Dominion in a 27-14 win. But only scoring 27 points in a game where they had over 500 yards of offense would have to be a disappointment in the eyes of Curt Cignetti and the Hoosiers. They will try to be more clinical in scoring range in this contest.
Quarterback Play
Indiana’s Fernando Mendoza managed a steady debut for the Hoosiers. He completed 18 of 31 for 193 yards and no interceptions. He was aided by a strong performance by the Indiana ground game but will need to be more productive through the air before Big Ten play begins. Kennesaw State’s Dexter Williams II’s 36% completion rate is a red flag going into this game. Sustaining drives will be a challenge for the Owls unless his passing improves.
Betting Trends & H2H
- Kennesaw State covered the spread in their season opener against Wake Forest.
- Indiana failed to cover the number against Old Dominion last week.
- Both of these teams went under the total in their first games of the 2025 season.
- This is the first time that Indiana and Kennesaw State have ever played in college football.
Kennesaw State vs Indiana Model Projection
Score Projection: Indiana 43 – Kennesaw State 14
Win Probability: Indiana 98%, Kennesaw State 2%
Final Thoughts
Indiana should have no problem rolling this week against a Kennesaw State team that is largely thought to be one of the worst teams in FBS football. The Hoosiers should rack up a ton of yards on offense for the second week in a row. The question will be whether Indiana can do enough in scoring range to put up a big number on the scoreboard. I think they will and that this game will go over the total on Saturday afternoon.
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- Source: https://ats.io/college-football/kennesaw-state-vs-indiana-pick-prediction-9-6-2025/465223/