The Baltimore Orioles and New York Yankees will square off on Saturday afternoon at Yankee Stadium. The Yankees carry momentum after a resounding 8–4 win over Baltimore the night before, as the Yankees enter the day in a tie with the Toronto Blue Jays in the AL East standings. Before these division rivals battle in the Bronx, continue reading to get my Orioles vs Yankees prediction for Saturday’s game.
Our Orioles vs Yankees Pick
- Pick: New York Yankees -1.5
- Confidence: 4/5
Game Snapshot
- Matchup: Baltimore Orioles vs New York Yankees
- Date & Time: Saturday, September 27, 2025, 1:05 PM ET
- Starting Pitchers: Tomoyuki Sugano (Orioles) vs Cam Schlittler (Yankees)
- Stadium: Yankee Stadium, Bronx, NY
- Broadcast: YES Network (Yankees), MASN (Orioles)
Key Storylines
Pitching matchup
Tomoyuki Sugano will get the start for the Orioles today. He enters this contest at 10-9 on the season and has a 4.54 ERA. Sugano has not generated many strikeouts this year. That has led to a lot of contact from opposing hitters and has been a big reason for his 30 home runs allowed on the year.
Cam Schlittler will take the hill for the Yankees in this important matchup for them. Schlittler is 3-3 on the season and has a very respectable 3.27 ERA. His strikeout rate is over one per inning and he is allowing under a hit per inning. The Yankees have a promising young arm in Schlittler to look forward to developing.
Recent team streaks
- The Yankees have won six straight games and are in a tie with the Blue Jays for first place in the AL East.
- Baltimore is 2-3 in its last five games and just wants to get to the finish line for the season.
Best Player Props
| Player | Prop |
|---|---|
| Aaron Judge | Over 0.5 HR |
| Giancarlo Stanton | Over 0.5 HR |
| Gunnar Henderson | Over 1.5 Total Bases |
Betting Trends & H2H
- The Yankees hold a 7-4 lead in their season series with Baltimore after winning Friday’s series opener.
- With Friday’s win, the Yankees have clinched a victory in their season series with Baltimore.
- The first game of this series went over its total, with 12 total runs scored.
Orioles vs Yankees Model Projection
Score Projection: Baltimore 3 – New York 5
Win Probability: Orioles 35%, Yankees 65%
Final Thoughts
I don’t see the Yankees having any problems getting the win in this game on Saturday afternoon. New York has something to play for at the end of the season and they have more than enough offensive talent to cover the runline. I’ll go with the Yankees to win this matchup by two runs or more, as they should keep the pressure on the Blue Jays to perform later in the day against the Tampa Bay Rays.
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- Source: https://ats.io/mlb/baltimore-orioles-vs-new-york-yankees-prediction-9-27-2025/468804/